Strain Fermentation Monitoring

Fermentation Monitoring is Unlocking the Full Potential of Biotechnology

Fermentation is a fundamental biological process that has been used for centuries to produce a wide range of products, including food, beverages, pharmaceuticals, and biofuels. Traditional methods of fermentation monitoring involve time-consuming and costly methods such as manual sampling and offline analysis. However, monitoring the fermentation process in real-time can be challenging due to the complex interactions between microorganisms, substrates, and environmental factors.

Figure 1: Graphical abstract of UV-Vis process monitoring. (Roberts J., et al. 2018)

CD Biosynsis recognizes the importance of fermentation monitoring and have developed innovative services to help unlock the full potential of biotechnology.

Our Services for Fermentation Monitoring

Real-time pH Monitoring

Our real-time pH monitoring service uses advanced sensing technologies to provide customers with accurate and reliable pH data. This allows customers to detect process deviations and make adjustments in real-time, ensuring optimal fermentation conditions.

• We use state-of-the-art pH sensors like pH sensors (e.g. glass electrode, membrane sensor), Optical pH sensors (e.g. fiber-optic sensor, fluorescence sensor), pH monitor probes (e.g. calibrated probes, multielement probes) to measure pH levels in the fermentation broth.
• The data is transmitted in real-time to our secure server for analysis and monitoring.
• Our team of experts reviews the data and alerts customers of any process deviations.

Online Glucose Monitoring

Our online glucose monitoring service provides customers with real-time glucose levels in the fermentation broth.

• We use advanced optical sensors like Optical glucose sensors (e.g. fiber-optic sensor, fluorescence sensor), Enzymatic glucose sensors (e.g. glucose oxidase, glucose dehydrogenase), Electrochemical glucose sensors (e.g. amperometric, potentiometric) to measure glucose levels in the fermentation broth.
• The data is transmitted in real-time to our secure server for analysis and monitoring.
• Our team of experts reviews the data and alerts customers of any process deviations.

Comprehensive Metabolomics Analysis

Our comprehensive metabolomics analysis service provides customers with a detailed understanding of the metabolites present in their fermentation broth.

• We use advanced analytical techniques such as gas chromatography, mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy to analyze the metabolome.
• The data is analyzed by our team of experts to identify and quantify metabolites.
• Customers receive a comprehensive report outlining the metabolome and any potential issues.

Data Analytics and Process Optimization

Our data analytics and process optimization service uses advanced data analytics tools and techniques to analyze the data generated from our sensing services.

• We use machine learning algorithms like machine learning algorithms (e.g. decision trees, support vector machines, neural networks), statistical process control (SPC), principal component analysis (PCA) and cluster analysis to analyze the data generated from our sensing services.
• The data is analyzed to identify trends, patterns, and potential issues.
• Customers receive a comprehensive report outlining the insights gained from the analysis and recommendations for process optimization.

Benefits of Our Approachs

• Expertise in biotechnology.
• Advanced sensing technologies.
• Data-driven insights.
• Customized solutions.

Fermentation monitoring is a critical aspect of biotechnology, and CD Biosynsis is at the forefront of this field. Our innovative services and expertise in fermentation science enable us to provide customers with high-quality monitoring services and tailored solutions that help unlock the full potential of biotechnology. Whether you are looking to optimize your fermentation process, improve productivity and efficiency, or develop new bioproducts, CD Biosynsis is your ideal partner. Contact us today to learn more about our services and how we can help you achieve your goals.

References

1. Roberts J., et al. The Use of UV-Vis Spectroscopy in Bioprocess and Fermentation Monitoring. Fermentation, 2018, 4(1): 18.
2. Pontius Katrin, et al. Automated Electrochemical Glucose Biosensor Platform as an Efficient Tool Toward On-Line Fermentation Monitoring: Novel Application Approaches and Insights. Frontiers in bioengineering and biotechnology, 2020, 8: 436.

Please note that all services are for research use only. Not intended for any clinical use.