Sterols have various important physiological functions, and their biosynthesis and function have been fully studied in eukaryotes. However, the synthesis and function of bacterial sterols are relatively poorly explored. There are several bacteria known to produce sterols from scratch, including aerobic methane oxidizing bacteria, floating mold, and various slime bacteria. Unlike eukaryotes, these bacteria mainly…
In recent years, there has been a trend in the skincare industry towards “presenting facts and reasoning” ingredients. Blue copper peptides, which have been dormant in the industry for many years, have become active in the public eye, along with their popularity and raw material prices. Since its usability has been explored by many brands…
The Mai brothers we are going to talk about today are not mainstream (mainly because they are expensive). But as everyone delves deeper into the ingredients and its own strength, adhering to the principle of “gold always shines”, Ergothiamine gradually becomes well-known and widely used. So today, I will take everyone together to get to…
Organisms use enzymes to decompose or synthesize substances under mild conditions, often without relying on toxic compounds or extreme high temperature conditions, making them known as “perfect chemists”. However, due to the complexity and variability of enzyme reaction mechanisms, designing their synthesis is one of the most challenging tasks in biochemistry. On February 22nd, David…
Enzymes are a class of highly functional biocatalysts that catalyze chemical reactions through complex active sites, greatly accelerating the reaction process and providing unparalleled selectivity. With the advancement of technologies such as DNA synthesis and sequencing, bioinformatics, and computational modeling, more and more natural enzymes with specific catalytic functions have been discovered. These enzymes have…
Evolution has produced multiple functional proteins that can precisely regulate cellular processes. In recent years, deep generation models have emerged, aiming to learn from this diversity and generate both effective and novel proteins, with the ultimate goal of customizing functionality to address today’s prominent challenges. When it comes to creating new proteins on computers,…
Raspberry ketone is the main aromatic compound of red raspberry, which has wide applications in cosmetics, food, and medicine. In recent years, raspberry ketone has attracted wide attention as a essence and dietary supplement. However, the natural abundance of raspberry ketone is low, with only 1-4 milligrams extracted from 1 kilogram of raspberry, making…
1) Introduction to L-malic acid Malic acid, also known as 2-hydroxysuccinic acid, has an asymmetric carbon hydroxysuccinic acid in its molecule, which has two stereoisomers and exists in three forms: L-malic acid, DL malic acid, and D-malic acid. It can be widely used in fields such as food and beverage, medicine, and chemical industry. Currently,…
The drawbacks of traditional microbial fermentation processes include the risk of contamination by harmful microorganisms, the inhibitory effect of high concentration carbon sources in the culture medium, microbial thermal sensitivity, and instability. And low yield and productivity, low substrate utilization efficiency, production of by-products and secondary metabolites, or high downstream processing costs. In order to…
The definition of synthetic biology is to use engineering ideas to modularize or create biological cells, enabling them to have the ability to synthesize compounds. Generalized synthetic biology actually refers to the extension of a series of downstream technologies based on DNA editing technology, including microbial metabolic engineering, enzyme engineering, gene editing services, cell therapy…