Case Study: AI-Driven Enzyme Engineering Revolutionizes Fabric & Household Care
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Amylase Design and Optimization for Dishwashing Detergents

Amylase Design and Optimization for Dishwashing Detergents

EnzymoGenius™, our advanced enzyme AI design platform, specializes in delivering comprehensive solutions for dishwashing detergent research, with a focus on harnessing the potential of amylases. Our services encompass a range of capabilities, enabling innovation and optimization throughout the key stages of detergent formulation. Through advanced enzymatic solutions, we facilitate breakthroughs in dishwashing efficiency and sustainability. 

Background

Amylases, primarily alpha and beta forms, continue to garner interest in dishwashing detergent applications and research, primarily due to their environment-friendly nature and prolific stain-removing abilities. They have the potential to significantly alter the dishwashing detergent industry landscape. The strategic implementation of these enzymes eradicates starch-based residue on utensils while promoting an eco-friendly washing alternative, hence minimizing the deleterious effects on the environment.

Comparison of amylase and surfactant interactions in detergent formulations.Fig 1. Comparison of amylase and surfactant interactions in detergent formulations. (Singh A, et al., 2018)

Amylases, primarily alpha and beta forms, continue to garner interest in dishwashing detergent applications and research, primarily due to their environment-friendly nature and prolific stain-removing abilities. They have the potential to significantly alter the dishwashing detergent industry landscape. The strategic implementation of these enzymes eradicates starch-based residue on utensils while promoting an eco-friendly washing alternative, hence minimizing the deleterious effects on the environment.

Products and Solutions Offering

Custom Products

  • Thermostable Amylases: Enzymes resistant to high temperatures, ideal for hot water dishwashing.
  • Alkaline Amylases: Amylases optimized for alkaline detergent formulations.
  • Stain-Specific Amylases: Tailored enzymes for the breakdown of specific food stains.
  • Multi-Substrate Amylases: Versatile enzymes that target a wide range of starch-based residues.
  • pH-Tolerant Amylases: Enzymes designed to perform effectively across varying pH levels.
  • Eco-Friendly Amylases: Sustainable enzyme options for green detergent development.

Custom Products

  • Enzyme Identification: Expertise in identifying amylases with optimal properties for dishwashing detergents.
  • Enzyme Engineering: Tailoring amylases to enhance their performance under specific detergent conditions.
  • Formulation Enhancement: Incorporating amylases to boost the efficacy of detergent formulations.
  • Sustainability Integration: Integrating amylases to improve the environmental footprint of dishwashing detergents.
  • Performance Testing: Rigorous evaluation of amylase-enhanced detergents for cleaning efficiency.

Services Process for Amylase Design and Optimization

1. Screening: Identifying amylases with potential properties from diverse sources.

2. Mutation and Engineering: Applying genetic modifications to enhance amylase efficiency.

3. Expression and Production: Efficiently producing the selected amylases at scale.

4. Characterization: Evaluating amylase properties under various conditions.

5. Formulation Integration: Incorporating amylases into detergent matrices.

6. Performance Testing: Rigorous evaluation to ensure improved dishwashing efficacy.

Technical Advantages

  • Molecular Modeling: Utilizing computational tools to predict amylase behavior and design modifications.
  • High-Throughput Screening: Streamlining the identification of suitable amylases.
  • Protein Expression Technologies: Ensuring efficient production of amylases.
  • Analytical Chemistry Techniques: Characterizing enzyme properties for optimization.
  • Bioprocess Engineering: Scaling up amylase production for commercial applications.
  • Green Chemistry Principles: Emphasizing eco-friendly approaches to detergent research.

CD Biosynsis is a pioneer in delivering enzyme-based solutions for the fabric & household care sector. Our suite of services covers enzyme identification, optimization, formulation, and compatibility testing. These solutions apply to various research areas, from enzyme kinetics to formulation chemistry, environmental impact, and enzyme engineering. Our technical advantages encompass enzyme profiling, high throughput screening, custom formulation, a sustainability focus, and a commitment to continuous research. Contact us to explore the limitless potential of enzyme-based solutions for cleaning and care.

Reference

  1. Singh, A.; et al. Comparative interaction study of amylase and surfactants for potential detergent formulation. Journal of Molecular Liquids. 2018, 261: 397-401.

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