Glucose Isomerase Design and Optimization for Carbohydrate Processing

EnzymoGenius™ is the leading artificial intelligence enzyme specialist. With a professional team of scientists, we have long been dedicated to providing researchers with targeted enzyme evolution and design services. For the food and beverage processing sector, especially for carbohydrate processing, we offer customized glucose isomerase solutions designed to enhance various key steps in carbohydrate processing, ensuring efficiency and precision.

Role of Glucose Isomerase in Carbohydrate Processing

Glucose isomerase, vital in carbohydrate processing, transforms glucose into fructose, crucial in industrial applications like high-fructose corn syrup (HFCS). It enhances food product sweetness and stability by converting glucose to fructose. Operating under mild conditions, it economically benefits large-scale carbohydrate conversion processes. Its action involves creating an enzymatic environment favoring intramolecular glucose rearrangement, resulting in fructose formation.

Fig. 1 Efficient conversion of glucose to fructose by endogenous polyamine spermine-assisted isomerization. (Kumar S, et al., 2020)

Research trends in glucose isomerase aim at boosting efficiency, stability, and specificity to meet food industry demands. Strategies involve optimizing catalytic activity through protein engineering, seeking improved variants from novel microbial sources, and using immobilization techniques for industrial operational stability. Advancements in bioprocess engineering target production scaling and cost reduction related to enzyme use. These trends highlight glucose isomerase's pivotal role in carbohydrate processing, showcasing ongoing innovation and optimization in enzymatic biocatalysis for industrial applications.

Products and Solutions Offering

Our Advantages

• Cutting-edge Artificial Intelligence (AI).
  Design and optimization of xylanase for baked goods processing.
• Advanced Molecular Biology Techniques.
  Including gene synthesis and cloning for enzyme production.
• High-Throughput Screening Tools.
  Facilitate the rapid assessment of enzyme variants, accelerating the optimization process.
• Analytical Chemistry Techniques.
  Such as mass spectrometry and chromatography for enzyme characterization and food product analysis.
• Computational Modeling.
  Simulate enzyme-substrate interactions and predict optimal conditions.

With a professional scientific team, CD Biosynsis has been dedicated to providing researchers with enzyme-directed evolution and design services. Our services cover the entire food and beverage processing spectrum, including food baking, brewing, dairy processing, vegetable and fruit processing, value-added by-products, and food ingredient development. Through the combined power of AI and synthetic biology, we can offer unrivaled advantages to improve productivity and product quality. If you are interested in the exclusive customized services for enzymes, please feel free to contact us.

Reference

1. Kumar, S.; et al. Efficient conversion of glucose into fructose via extraction-assisted isomerization catalyzed by endogenous polyamine spermine in the aqueous phase. ACS Omega. 2020, 5(5): 2406–2418.