Case Study: AI-Driven Enzyme Engineering Revolutionizes Fabric & Household Care
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Mannanase Design and Optimization for Dishwashing Detergents

Mannanase Design and Optimization for Dishwashing Detergents

EnzymoGenius™, our advanced enzyme AI design platform, specializes in delivering a suite of mannanase-based services and solutions that play a pivotal role in advancing dishwashing detergent research. These cutting-edge offerings are tailored to address the complex challenges and demands of this field. Through our expertise and state-of-the-art technologies, we facilitate groundbreaking developments in the dishwashing detergent industry.

Background

Interest in applications and research on mannanases in dishwashing detergents has intensified due to their versatile biotechnological applications. Mannanases, an integral part of the glycoside hydrolase family, are fundamental in the hydrolysis of beta-D-mannans, a distinguishing component of vegetable oil stains. Furthermore, mannanases endow dishwashing detergents with improved stain-removal capabilities. An emerging hotspot for research in this field is in eco-friendly and sustainable products, with mannanases playing a critical role. Studies delve into the exploration of microbial sources for mannanase production, augmenting the yield and the catalytic efficiency. Research from various parts of the globe also spotlights the utilization of mannanases in producing biofuels, contributing towards greener alternatives. In conclusion, the application of mannanases in dishwashing detergents reveals intriguing potential in the sector of industrial biotechnology, from stain removal to environmental sustainability.

Comparison of amylase and surfactant interactions in detergent formulations.Fig 1. Optimization of mannanase production and characterization from Aspergillus niger. (Jana U K, et al., 2018)

Products and Solutions Offering

Custom Products

  • Mannanase Enzyme Variants: We offer a range of mannanase enzyme variants tailored to different detergent formulations and cleaning requirements.
  • Enzyme Stabilizers: Our stabilizers enhance the shelf life and performance of mannanase enzymes in detergent products.
  • Detergent Additives: Specialized mannanase-based additives that improve the overall cleaning efficiency of dishwashing detergents.
  • Enzyme Assays and Testing Kits: Comprehensive kits and assays for evaluating the enzymatic activity of mannanases in detergent formulations.

Custom Products

  • Stain Removal Enhancement: Mannanases can effectively break down complex polysaccharides found in various food stains and greasy residues, enabling more efficient stain removal in dishwashing detergents.
  • Enzyme Stability Improvement: Our solutions optimize the stability of mannanases under varying pH and temperature conditions, ensuring consistent enzyme performance in detergents.
  • Eco-Friendly Formulations: Mannanases aid in formulating environmentally friendly detergents by accelerating the degradation of organic matter, reducing the need for harsh chemicals.
  • Protein Soil Cleaning: These enzymes are engineered to target protein-based soils, ensuring the removal of tough, proteinaceous food residues.
  • Reduced Water Consumption: By facilitating faster soil removal, mannanases reduce the need for excessive rinsing, resulting in water and energy savings.

Services Process for Mannanase Design and Optimization

1. Substrate Specificity Engineering: Mannanase enzymes are modified to target specific types of stains and soils commonly encountered in dishwashing.

2. pH and Temperature Tolerance: Optimization for stability and efficacy across a range of pH levels and temperatures ensures consistent enzyme performance.

3. Enhanced Catalytic Efficiency: Through rational design and mutagenesis, mannanases are improved to work faster and more effectively.

4. Formulation Integration: We integrate mannanases seamlessly into detergent formulations, ensuring compatibility and maximizing cleaning power.

Technical Advantages

  • Enzyme Engineering: Utilizing the latest techniques in enzyme engineering to modify and enhance mannanase enzymes for superior performance.
  • High-Throughput Screening: Employing automated screening methods to rapidly identify the most efficient mannanase variants.
  • Bioinformatics and Computational Biology: Harnessing the power of computational tools for enzyme design and prediction of substrate specificities.
  • Protein Expression Systems: Utilizing advanced expression systems to produce mannanase enzymes at scale.
  • Formulation Chemistry: Expertise in detergent chemistry to ensure effective integration of mannanases into detergent products.

CD Biosynsis is a pioneer in delivering enzyme-based solutions for the fabric & household care sector. Our suite of services covers enzyme identification, optimization, formulation, and compatibility testing. These solutions apply to various research areas, from enzyme kinetics to formulation chemistry, environmental impact, and enzyme engineering. Our technical advantages encompass enzyme profiling, high throughput screening, custom formulation, a sustainability focus, and a commitment to continuous research. Contact us to explore the limitless potential of enzyme-based solutions for cleaning and care.

Reference

  1. Jana, U. K.; et al. Production optimization and characterization of mannooligosaccharide generating β-mannanase from Aspergillus oryzae. Bioresource Technology. 2018, 268: 308-314.

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