RNA Polymerase Design and Optimization

Our advanced enzyme AI design platform - EnzymoGenius™ specializes in providing a comprehensive suite of services that encompasses custom RNA polymerase products and innovative solutions that empower researchers and industry professionals to drive advancements in genetic research, drug development, and therapeutic applications.

Background

RNA polymerase stands as the pivotal enzymatic component responsible for transcription within cellular processes. It catalyzes the synthesis of RNA strands using a DNA template, facilitating the translation of genetic information encoded in DNA into functional RNA molecules. The RNA polymerase achieves this through a multi-step process that begins with promoter recognition, followed by initiation, elongation, and ultimately, termination. This complex mechanism is finely orchestrated and plays a crucial role in the regulation of gene expression.

Fig 1. Repair of DNA double-strand breaks by homologous recombination using RNA polymerase III. (Liu S, et al., 2021)

Products and Solutions Offering

Technical Advantages

• Machine Learning Algorithms. Employing state-of-the-art machine learning techniques to optimize sequence design and enzyme selection.
• Machine Learning and AI. Harnessing advanced AI algorithms for RNA polymerase design.
• Genomic Data Analysis. Utilizing vast genomic datasets for sequence optimization.
• High-Throughput Screening. Employing high-throughput assays for RNA polymerase validation.
• Molecular Biology Techniques. Applying cutting-edge molecular biology tools for RNA polymerase customization.
• Bioinformatics. Leveraging bioinformatics tools to decipher genetic information and design optimal RNA polymerase variants.
• Expression Systems. Developing and utilizing state-of-the-art expression systems for RNA polymerase production.

With a focus on precision, efficiency, and customization, CD Biosynsis empowers researchers and industry professionals to advance genetic research, drug development, and therapeutic applications. Our cutting-edge technologies, including AI, genomic data analysis, high-throughput screening, and molecular biology techniques, ensure that your projects benefit from the latest innovations. Contact us to explore our AI-driven RNA polymerase variants, kits, expression systems, and mutants, along with customized solutions for enhanced promoter recognition, transcription efficiency, and regulatory sequence identification.

Reference

1. Liu, S.; et al. RNA polymerase III is required for the repair of DNA double-strand breaks by homologous recombination. Cell. 2021, 184(5): 1314-1329.