ACAT Inhibitors

ACAT inhibitors are a group of pharmaceutical compounds that play a crucial role in lipid metabolism regulation ACAT short for Acyl-CoA cholesterol acyltransferase is an enzyme that catalyzes the formation of cholesterol esters which are essential for the storage and transport of cholesterol within the body ACAT inhibitors work by blocking the activity of this enzyme preventing the accumulation of cholesterol esters in various tissues particularly in the arteries By reducing the production of cholesterol esters ACAT inhibitors aid in lowering overall cholesterol levels and have shown promising potential in managing cardiovascular diseases Our company offers a range of advanced ACAT inhibitors that are designed to provide effective and targeted therapy for individuals at risk of or already suffering from conditions related to elevated cholesterol levels

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Products Application Supporting Data Resources Related Products

Products

Catalog Number	Chemical Name	CAS #	Price
BC-0616	Naringenin	480-41-1	Online Inquiry
BC-0628	Pellitorine	18836-52-7	Online Inquiry
EI-0262	Avasimibe	166518-60-1	Online Inquiry
EI-1268	K-604, ACAT-1 inhibitor	561023-90-3	Online Inquiry
EI-1707	Penicillide	55303-92-9	Online Inquiry
EI-1837	Pyripyropene A	147444-03-9	Online Inquiry
EI-2149	Terpendole C	156967-65-6	Online Inquiry
EI-2182	TMP-153	128831-46-9	Online Inquiry

Application

ACAT inhibitors are a powerful tool in the field of cardiovascular research and drug development By blocking the activity of acyl-CoA:cholesterol acyltransferase (ACAT) these inhibitors effectively reduce the production of cholesterol esters leading to decreased levels of LDL or "bad" cholesterol in the bloodstream This application of ACAT inhibitors holds great promise for the treatment and prevention of atherosclerosis a condition characterized by the buildup of cholesterol in arterial walls and a major risk factor for cardiovascular disease

Furthermore ACAT inhibitors have also shown potential in the field of neurology Studies have suggested that inhibiting ACAT activity may help alleviate the accumulation of amyloid-beta plaques in the brain which is a hallmark of Alzheimer's disease By preventing the formation of these plaques ACAT inhibitors have the potential to slow down or even halt the progression of this devastating neurodegenerative disorder

In addition to their cardiovascular and neurological applications ACAT inhibitors have also been investigated in the field of dermatology By inhibiting the production of cholesterol esters these inhibitors have shown promise in reducing sebum secretion and inflammation associated with certain skin conditions such as acne This potential therapeutic use of ACAT inhibitors opens up new avenues for the development of targeted treatments for individuals struggling with skin disorders

Overall the diverse applications of ACAT inhibitors demonstrate their significant potential as a tool in biomedical research and the development of novel treatments for a range of diseases and conditions making them a valuable asset in the field of biological sciences

Supporting Data

Resources

Please note that all services are for research use only. Not intended for any clinical use.

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