Bacterial Synthetic Biology

CD Biosynsis offers customized solutions for bacterial synthetic biology to help researchers around the world facilitate their cutting-edge research and overcome the challenges. We provide advanced techniques and powerful tools to help our customers solve any problems encountered in their projects and bring breakthrough ideas to fruition.

Introduction to Bacterial Synthetic Biology

Synthetic Biology is an emerging field that combines engineering principles with biological parts to modify existing biological systems by designing novel, modular, and tunable gene products or genetic circuits. One of the main aspects of synthetic biology is the assembly of natural and novel engineered parts into biological circuits for desired cellular functions and programmed cell behaviors. In recent years, synthetic biologists have become increasingly interested in developing tools for engineering microbial genomes. This has given rise to the field of bacterial synthetic biology, a scientific discipline that uses molecular biology and engineering tools to deal with the synthesis of part or whole bacteria that do not exist in nature in this form. The applications of synthetic biology in bacteria have broadly ranged from the construction of small genetic circuits for desired gene/pathway functions to whole genome engineering.

The main objective of bacterial synthetic biology is to design, engineer, and construct new synthetic bacterial cells that do not exist in nature as well as to re-engineer existing bacteria. Precise changes in bacterial genomes have resulted in the creation of desired biological traits in engineered strains. Synthetic biology offers a novel platform for bridging the gap between basic and translational research. It is expected that the construction of novel genetic circuits in bacterial will greatly benefit from the data generated by 'omics' approaches and the multidisciplinary nature of synthetic biology. Advances in synthetic biology and its combination with newly developed genome engineering tools have further enabled the use of engineered bacteria to address some of the global challenges, from renewable energy to global health.

Figure 1. A representation of the design process of traditional genetic engineering (a) and synthetic biology (b). (Leonard E, et al., 2008)

Applications

Our Solutions

CD Biosynsis offers integrated solutions for specific purposes and a wide range of applications to help customers overcome the challenges of their bacterial synthetic biology projects.

CD Biosynsis is committed to developing services and products that cover a wide range of steps in the synthetic biology workflow. We are confident in the validity and reproducibility of the results we deliver because all of our services and products are based on reliable technologies and optimized protocols to meet high standards.

To start your synthetic biology projects, please feel free to contact us for more details. Our experienced scientific team of biologists, bioinformatics, and chemists are available for on-demand customer assistance to help you with any concerns you may have.

References

1. Leonard E, et al. Engineering microbes with synthetic biology frameworks. Trends in biotechnology, 2008, 26(12): 674-681.
2. Borkowski O, et al. Overloaded and stressed: whole-cell considerations for bacterial synthetic biology. Current opinion in microbiology, 2016, 33: 123-130.

Please note that all services are for research use only. Not intended for any clinical use.