Biocontainment Strategies in Strains

The Importance of Biocontainment

In the field of synthetic biology, genetically modified organisms (GMOs) have been engineered to produce a variety of products at an industrial scale. However, concerns have been raised surrounding the ecological risks associated with the release of GMOs outside of controlled environments. Biocontainment systems are needed to neutralize these GMOs and prevent them from causing harm to the environment. In addition, alternative selection markers are needed to replace costly and risky antibiotics.

CD Biosynsis is a leading company in the field of synthetic biology, offering a wide range of services related to biocontainment strategies in strains. Our team of experts has extensive experience in this field, and we are committed to providing innovative and effective solutions to our clients.

Figure 1: Biocontainment strategies and biosafety guidelines. (Zhu Xueying, et al. 2023)

Our Services for Biocontainment Strategies

CD Biosynsis offers a comprehensive range of services related to biocontainment strategies in strains, providing customized solutions that meet the specific needs of our clients. Our services include:

Development of Biocontainment Strains

Our team of experts specializes in the development of biocontainment strains that are engineered to be sensitive to specific selection agents, such as fluoride. We can customize the strains to meet the specific needs of our clients, ensuring that they are stringent and easily implemented.

Our development process includes genetic engineering of the target organism, followed by testing to ensure its effectiveness. We use a range of techniques to evaluate the performance of biocontainment strains, including growth inhibition assays and escape rate analysis.

DNA Vector Design and Construction

We offer DNA vector design and construction services for the development of biocontainment strains. Our vectors are designed to enable the use of fluoride as a selection agent, providing an alternative to antibiotics. Our vectors are cost-effective and eliminate the risks associated with propagating antibiotic resistance.

Our DNA vector design and construction process includes consultation with the client to understand their specific needs and goals. We then design and construct the vectors using the latest technologies and techniques.

Benchmarking and Testing

We provide benchmarking and testing services for biocontainment strains to ensure their effectiveness. Our team uses a range of techniques to evaluate the performance of biocontainment strains, including growth inhibition assays and escape rate analysis.

We also provide consultation and support throughout the benchmarking and testing process, working closely with our clients to ensure that we deliver the solutions they need.

Consultation and Support

At CD Biosynsis, we understand that every client has unique needs and goals. That's why we offer consultation and support services throughout the biocontainment process.

Our Advantages

• Experience and Expertise
• Customization and Flexibility
• Quality and Reliability
• Cost-effectiveness

CD Biosynsis offers a comprehensive range of services related to biocontainment strategies in strains, providing customized solutions that meet the specific needs of our clients. Our services include the development of biocontainment strains, DNA vector design and construction, benchmarking and testing, and consultation and support. We use the latest technologies and techniques to ensure the quality and reliability of our solutions, and we are committed to delivering value for money. With our experience, expertise, and commitment to excellence, CD Biosynsis is the ideal partner for biocontainment strategies in strains. Contact us today to learn more.

References

1. Zhu X.Y., et al. Current advances of biocontainment strategy in synthetic biology. Chinese Journal of Chemical Engineering, 2023, 56: 141-151.
2. Asin-Garcia, E., et al. Phosphite synthetic auxotrophy as an effective biocontainment strategy for the industrial chassis Pseudomonas putida. Cell Microbial Cell Factories, 2022, 21: 156.

Please note that all services are for research use only. Not intended for any clinical use.