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Cas9 Expressing Rat cardiomyocytes

Catalog Number: GEC0029

Price:
$1397.14
Specifications Overview Application Downloads Related products

Specifications

Product Information
Product Name Cas9 Expressing Rat cardiomyocytes
Specification 1*10^6
System circulatory system
Resistance hygro
Cas9 expression detection Provided
Cell name H9c2(2-1)-CAS9
Cell morphology Myoblast
passage ratio 1:3~1:4
Species expression gene Rat
Expressed Gene Cas9
Properties
Construction method Viral method
Mycoplasma detection negative
Storage and transportation Dry ice transportation; Store in liquid nitrogen
Culture system 90% DMEM+10% FBS

Overview

H9c2(2-1)-CAS9 is an advanced biological reagent derived from the H9c2 cell line which is a rat cardiac myoblast model widely utilized in cardiovascular research This product combines the characteristics of the H9c2 cell line with CRISPR-associated protein 9 (Cas9) technology enabling precise genome editing and functional analysis of cardiac genes H9c2(2-1)-CAS9 is essential for scientists aiming to elucidate the genetic underpinnings of cardiac diseases facilitating targeted modifications to study gene function regulatory networks and potential therapeutic pathways

The key mechanism underpinning H9c2(2-1)-CAS9 is its ability to utilize the CRISPR-Cas9 system for gene editing allowing for site-specific modifications through the introduction of double-strand breaks at predetermined genomic locations This precision not only enhances the understanding of cardiac biology but also supports the development of gene therapies aimed at ameliorating cardiac dysfunctions

The scientific importance of this product in both research and clinical settings cannot be overstated It serves as a powerful tool for generating disease models that mimic specific genetic conditions thus accelerating the path toward novel cardiac therapeutics By enabling targeted gene editing H9c2(2-1)-CAS9 offers researchers a streamlined approach to investigate gene functions in a biologically relevant environment paving the way for new cardiovascular interventions

Compared to traditional gene knockout or knock-in approaches H9c2(2-1)-CAS9 stands out due to its efficiency versatility and reduced off-target effects This product allows researchers to achieve desired genetic modifications with enhanced reliability saving valuable time and resources in experimental workflows

For researchers and clinicians focused on advancing cardiac health H9c2(2-1)-CAS9 represents an invaluable resource that bridges basic science and translational medicine Its capacity to facilitate groundbreaking discoveries in cardiac biology underscores its significance in the ever-evolving landscape of biomedical research

At [Your Company Name] we take pride in our expertise in developing cutting-edge biological products that empower researchers to push the frontiers of science Our commitment to quality and innovation makes H9c2(2-1)-CAS9 a trusted choice for those seeking to make impactful contributions to cardiovascular research

Application

H9c2(2-1)-CAS9 is a powerful tool primarily used in genetic engineering and cellular research particularly in cardiac biology This cell line derived from rat embryonic heart tissue serves as an excellent model for studying cardiac development function and disease mechanisms Researchers utilize H9c2(2-1)-CAS9 for CRISPR-Cas9 gene editing applications to investigate gene function and regulation related to cardiomyocyte hypertrophy and apoptosis

In experimental contexts this cell line is particularly useful for assessing the outcomes of targeted gene edits on cell survival and proliferation under varied stress conditions such as hypoxia or ischemia By incorporating H9c2(2-1)-CAS9 into workflows researchers can efficiently generate knockout models allowing for the elucidation of gene roles in cardiac responses

The practical benefits of using H9c2(2-1)-CAS9 include enhanced reproducibility of results and the ability to perform high-throughput screening in a standardized environment Moreover the established protocols for transfection and gene editing demonstrate significant efficiency making it an ideal candidate for labs focusing on cardiovascular research

Downloads

Please note that all services are for research use only. Not intended for any clinical use.

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