CASP2 Knockout cell line （Hep G2）

The CASP2 Knockout cell line (Hep G2) serves as a vital tool in cancer research particularly in understanding apoptosis and its role in tumorigenesis This product is primarily used in the study of liver cancer mechanisms exploring the effects of CASP2 deletion on cellular responses to chemotherapy agents In specific experimental contexts researchers can utilize this cell line to investigate altered pathways of cell survival and resistance in response to drug-induced stress providing insights into therapeutic vulnerabilities

Implementing the CASP2 Knockout cell line in laboratory workflows involves transfection protocols for gene editing and subsequent validation through Western blotting or PCR This cell line enables researchers to dissect the underlying mechanisms of CASP2’s impact on apoptosis facilitating a more profound understanding of its role in hepatocyte function

The practical benefits of employing this knockout model include enhanced specificity in studying gene function and a clearer definition of potential drug targets Furthermore this product excels in high-throughput screening assays allowing for efficient examination of pharmacological responses and gene modulation techniques in liver cancer studies