CD Caspase-3 Assay Kit

Catalog Number: AKBA510

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$867

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Specifications

Product Information
Product Name	CD Caspase-3 Assay Kit
Applications	For quantitative determination of the apoptosis target caspase-3 activity and HTS screen for apoptosis inducers and inhibitors.
Features	Safe. Non-radioactive assay. Convenient and high-throughput. Homogeneous “mix-incubate-measure” type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day.
Detection Method	FL400/490nm
Sample Type	Cell and tissue lysate
Species	All
Assay Time	60 min
Expiration Date	12 months
Description	Caspases are members of the aspartate-specific cysteinyl protease family that play a central role in apoptosis. Apoptosis is involved in a variety of physiological and pathological events, ranging from normal fetal development to diseases such as cancer, organ failure, and neurodegenerative diseases. Caspase-3 is key biomarker in the assessment of apoptosis and in understanding mechanism of apoptosis induction. CD Caspase-3 Assay Kit provides a convenient means to measure caspase-3 activity in biological samples. In the assay, a specific substrate (N-Ac-DEVD-AFC) is cleaved by active caspase-3, forming a highly fluorescent product.The fluorescence intensity (λex/em = 400/490nm) is proportional to the caspase-3 activity.
Shipping Conditions	Shipping: RT
Storage	Storage: -20°C upon receipt

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