CD Hyaluronidase Inhibitor Screening Assay Kit

Catalog Number: AKBA236

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$1497

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Product Information
Product Name	CD Hyaluronidase Inhibitor Screening Assay Kit
Applications	For evaluation and high-throughput screen (HTS) of hyaluronidase modulators.
Features	Rapid and reliable. The entire assay can be completed in 30 min. Simple and Convenient. Simple procedure with an enzymatic reaction and addition of stop reagent. No wash or reagent transfer steps are involved. Robust and amenable to HTS. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day.
Detection Method	Turbidimetric (OD 600nm)
Sample Type	Compounds that affect hyaluronidase activity
Species	All
Assay Time	30 min
Expiration Date	12 months
Description	HYALURONIDASES are a family of enzymes that catalyze the degradation of the glycosaminoglycan, hyaluronic acid. Hyaluronic acid is one of the major constituents of the extracellular matrix in organisms where it contributes to both cell proliferation and migration. The role of hyaluronidases in breaking down this key factor in cell proliferation makes them a possible target for cancer treatment. One hypothesis is that increased hyaluronidase may help prevent tumor invasion by breaking down the extracellular matrix needed for tumor expansion. Conversely, decreasing hyaluronidase activity might prevent metastasis by stopping cancer cells from escaping primary tumor masses. The study to determine hyaluronidases’ exact role in cancer pathology is still ongoing.BioAssay Systems’ Hyaluronidase Inhibitor Screening Assay Kit uses a two-step turbidimetric reaction to measure hyaluronidase activity by the amount of hyaluronic acid that is hydrolyzed. A stop reagent halts the enzymatic reaction and forms turbidity with any residual hyaluronic acid in the well. The decrease in turbidity at 600 nm is directly proportional to hyaluronidase activity in the sample.
Shipping Conditions	Shipping: RT
Storage	Storage: -20°C upon receipt

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