Product Information | |
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Product Name | CD Urokinase Inhibitor Screening Assay Kit |
Applications | For evaluation of drugs and screening potential inhibitors of urokinase. |
Features | Safe. Non-radioactive assay. Fast. Assay is completed within a 30 minute reaction time. Homogeneous “mix-incubate-measure” type assay. Can be readily automated to assay thousands of samples per day. |
Detection Method | FL380/450nm |
Sample Type | Compounds that affect urokinase activity |
Species | All |
Assay Time | 30min |
Limit of Detection | 0.04 U/L |
Expiration Date | 12 months |
Description | UROKINASE PLASMINOGEN ACTIVATOR (urokinase, uPA) is a key serine protease involved in the degradation of the extracellular matrix that catalyzes the conversion of plasminogen to active plasmin. It acts as a thrombolytic agent to break up blood clots and when over-expressed, has been reported to influence the growth of certain malignant tumors (breast, prostate, etc.). BioAssay Systems’ DUKI-100 Kit provides a convenient fluorimetric means to screen for potential urokinase inhibitors. In this assay, the fluorimetric substrate reacts with urokinase and an inhibitor will decrease the fluorescence at λex/em = 380/450 nm. |
Shipping Conditions | Shipping: RT |
Storage | Storage: -20°C upon receipt |
Please note that all services are for research use only. Not intended for any clinical use.
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