Biosynthesis Cell free system

CD Biosynsis harnesses the transformative power of the Cell-Free System to catalyze innovation across the biotech landscape. With an unwavering focus on precision, quality, and versatility, we empower researchers and biotech entities to explore new horizons and unlock the full potential of molecular biology. Join us on the journey to redefine the future of biotechnology through our pioneering Cell-Free System Services.

Introduction to Cell Free System

The Cell-Free System, a groundbreaking technology in biotechnology, has gained prominence for its capability to decouple molecular processes from cellular environments. This innovative approach enables the in vitro reconstitution of biological reactions, offering unprecedented control and versatility. By liberating essential cellular components, such as ribosomes and transcriptional machinery, from intact cells, the Cell-Free System catalyzes diverse applications across the biotech landscape.

Fig 1. Engineering protein, metabolism and artificial cell in the open cell-free system. (Lu Y, 2017)

Current Research Status of Cell-Free System

In the contemporary scientific landscape, the Cell-Free System has witnessed a meteoric rise in research interest and application. Researchers worldwide have leveraged this technology to tackle a diverse array of biological challenges. Its adaptability and versatility have enabled advancements in fields such as synthetic biology, structural biology, and biopharmaceuticals. This technology has not only broadened the horizons of protein synthesis but has also found applications in genome engineering and metabolic pathway characterization.

Technologies Involved in Cell-Free System

Our Cell-Free System leverages an array of advanced technologies, categorized into several key areas:

• Transcription and Translation. Utilizes transcription machinery (RNA polymerases) and translation machinery (ribosomes) for protein synthesis.
• Cell Lysates. Extracts cellular components, providing the necessary cellular machinery for in vitro reactions.
• Cell-Free Extracts. Tailored extracts designed for specific applications.
• Customized Buffers. Precisely formulated buffers to optimize protein synthesis conditions.
• Molecular Cloning. Employed for the preparation of templates necessary for protein synthesis.

Service Offering

CD Biosynsis offers a spectrum of services underpinned by the transformative capabilities of the Cell-Free System. These services include:

• Functional Assays

Enabling rigorous validation of protein functionality and high-throughput drug screening.

• Protein Expression

Facilitating high-yield protein production for therapeutic and research purposes.

• Metabolic Pathway Analysis

Unveiling intricate metabolic networks for bioprocess optimization.

• Genome Editing

Precise manipulation of genetic material for biotechnological advancements.

• Antibody Production

Streamlined generation of monoclonal antibodies for diagnostics and therapeutics.

• RNA and DNA Synthesis

Reliable synthesis of nucleic acids for a multitude of applications.

• Protein Engineering

Tailored modification and design of proteins for specific functions.

Advantages of Our Cell-Free System

• Scalability. Adaptable to both small-scale research projects and large-scale industrial applications.
• High Yield. Achieves rapid, high-yield protein production, ideal for biopharmaceutical development.
• Precise Control. Fine-tuned control over reaction conditions for optimal outcomes.
• Versatility. Suitable for a wide spectrum of applications, from enzyme characterization to drug discovery.
• Minimal Contamination. Minimizes the risk of cellular contaminants, ensuring purity of results.
• Compatibility. Adaptable to various substrates and templates, including plasmids and linear DNA.

CD Biosynsis offers a wide range of cutting-edge technologies and has an experienced scientific team of biologists, bioinformaticians, and chemists dedicated to helping synthetic biology researchers around the world solve any challenges they encounter in their projects. If you have any specific needs, please feel free to contact us for more details.

Reference

1. Lu, Y. Cell-free synthetic biology: Engineering in an open world. Synthetic and systems biotechnology. 2017, 2(1), 23-27.

Please note that all services are for research use only. Not intended for any clinical use.