Cellular Analysis

CD Biosynsis provides comprehensive cellular analysis for the test phase of synthetic biology to help researchers around the world facilitate their cutting-edge research. Equipment with an advanced technology platform and powerful synthetic biology tools, we have the ability to help bring diverse synthetic biology applications and creative ideas to fruition.

Introduction to Cellular Analysis

Synthetic biology has pioneered revolutionary approaches that influence how key questions in cell biology are addressed. Synthetic biology has enabled the study of cellular and molecular biology by advancing the design of genetic devices. Synthetic biology breakthroughs have also facilitated the engineering of genetic circuits to reprogram cells with dynamic gene expression and novel biological functions. Moreover, synthetic biology tools can be used to complement natural cell systems by providing engineered molecules with specific activities and model cell systems to mimic complex regulatory processes. These tools are being applied to effectively study a variety of cellular processes, regulatory networks, and multicellular interactions. Advances in automation technology and computational tools will further expand the ability to probe cellular mechanisms with genetic devices to better understand the cell.

In order to achieve flexible, precise, and comprehensive control over gene expression and cellular development, new endeavors have shifted from bacterial engineering to mammalian gene regulation. More and more new and complex genetic devices have been used to explore cellular mechanisms such as alternative RNAi, splicing, and epigenetics. The ability to regulate complex regulatory networks such as cell signaling, cell communication, cell cycle, and cell differentiation has been achieved. Synthetic biology has been used to deeply understand cellular mechanisms and advance cell biology research.

Figure 1. Tools and approaches for studying multicellular behavior. (Mathur M, et al., 2017)

Featured Services

CD Biosynsis offers a complete set of tools for cellular analysis and synthetic biology to help our customers overcome the challenges in synthetic biology. Browse our featured services below or use our online inquiry form to get more information.

Cell Type Identification

A range of synthetic biology tools has been developed to overcome the limitations of cellular reprogramming and provide new modes for cell fate engineering. Cellular reprogramming is the progress that drives cells from one stable identity to new cell fate. CD Biosynsis provides specialized cell type identification services based on advanced techniques, such as single-cell RNA sequencing and automation.

Cell-To-Cell Communication

Cell-to-cell communication plays a critical role in the information exchange between specialized cells within multicellular organisms. CD Biosynsis offers synthetic biology techniques to assess the underlying complex regulatory networks of multiple interacting genes and model cell-to-cell communication networks.

Cellular Development and Differentiation

Cells undergo growth and division during normal cellular development. Genetic devices have been used to examine both cell cycle progression and proliferation. CD Biosynsis provides both basic experimental studies and advanced synthetic biology tools for the study and analysis of cellular development and differentiation.

Cell Signaling

Cell signaling is responsible for enabling cells and organisms to respond properly to diverse environmental signals. CD Biosynsis provides synthetic biology tools that introduce precise and controlled perturbations into cell signaling pathways to analyze the downstream biological behavior.

CD Biosynsis offers a variety of cutting-edge techniques to customize services for individual customer specifications. Our experienced scientific team of biologists, bioinformatics, and chemists is dedicated to helpinging our customers solve any problems encountered in their synthetic biology projects.

If you are interested in our services or have any specific needs, please feel free to contact us for more details.

References

1. Mathur M, et al. Mammalian synthetic biology for studying the cell. Journal of Cell Biology, 2017, 216(1): 73-82.
2. Safaei M, et al. Synthetic biology in various cellular and molecular fields: applications, limitations, and perspective. Molecular Biology Reports, 2020: 1-10.

Please note that all services are for research use only. Not intended for any clinical use.