Biosynthesis Experimental Redesign

CD Biosynsis provides experimental redesign services for the "learn" phase of synthetic biology to help researchers around the world facilitate their cutting-edge research. We have the ability and extensive experience to help bring diverse synthetic biology applications and creative ideas to fruition.

Introduction to Experimental Redesign

Synthetic biology combines biology, engineering, and computer science. It is a young discipline that is still in its early stages of development. Synthetic biology allows for reliable programming of cellular behavior and seeks ways to redesign biology from engineering and computation. The primary goals of synthetic biology are to generate new chemicals, improve human health, and solve environmental problems. The need for synthetic biology is real and synthetic biology approaches will permeate the biological community in the near future.

Synthetic biology has influenced the studies of biological systems in terms of their value for biological redesign. In synthetic biology, meeting design specifications is a major challenge because it often highlights the real difficulties of a given biological problem. Design to specification and extensive pre-experiment planning to avoid excessive trial and error are paramount ideas. Synthetic biologists need to keep track of gene expression, protein structure, metabolism, function, and all the other things that biology modulates in the course of evolution. As a result, most synthetic biology seems to involve repeated and intensive borrowing from nature. Experimental redesign at the learn stage plays an important role in efficiently exploring different combinations of design choices by running a relatively small number of tests.

Figure 1. Integrated design-build-test-learn cycles in synthetic biology encompassing whole-cell model-guided approaches, and relative applications. (Marucci L, et al., 2020)

Service Offering

CD Biosynsis offers customized experimental redesign services for synthetic biology to help our customers overcome the challenges. Browse our services below or use our online inquiry form to get more information.

CD Biosynsis offers customized services for individual customer specifications. Our experienced scientific team of biologists, bioinformatics, and chemists is dedicated to helpinging our customers solve any problems encountered in their synthetic biology projects.

If you are interested in our services or have any specific needs, please feel free to contact us for more details.

References

1. Marucci L, et al. Computer-aided whole-cell design: taking a holistic approach by integrating synthetic with systems biology. arXiv preprint arXiv, 2020, 2006.02720.
2. Way J C, et al. Integrating biological redesign: where synthetic biology came from and where it needs to go. Cell, 2014, 157(1): 151-161.

Please note that all services are for research use only. Not intended for any clinical use.