Genome editing has evolved into a transformative field, driven by a diverse array of products that enable precise manipulation of genetic material. These products cater to a range of applications, from targeted gene editing within cellular systems to in vitro modifications of DNA. Here's a comprehensive overview of some prominent Genome Editing products:
1.CRISPR-Cas9 Cell Lines:
Purpose: Facilitates efficient and targeted gene editing within cellular systems.
Description: Engineered cell lines expressing the CRISPR-Cas9 system for specific and controlled genomic modifications.
2.sgRNA Synthesis Kit:
Purpose: Allows the production of synthetic guide RNAs (sgRNAs) for guiding Cas9 or other nucleases to target DNA sequences.
Description: Kits providing the necessary reagents for the synthesis of sgRNAs, a crucial component in the CRISPR-Cas system.
3.TALEN Expression Vectors:
Purpose: Enables targeted genome editing through the introduction of customizable Transcription Activator-Like Effector Nucleases (TALENs).
Description: Plasmids or vectors containing TALEN sequences for efficient and programmable genome modifications.
4.ZFN (Zinc Finger Nuclease) Kits:
Purpose: Provides components for using ZFNs, allowing researchers to induce site-specific double-strand breaks for genome engineering.
Description: Kits containing ZFNs for targeted DNA cleavage and subsequent modifications with high precision.
5.CRISPR-Cas12 Cell Lines:
Purpose: Engineered cell lines expressing Cas12 for targeted DNA cleavage with distinct advantages over Cas9.
Description: Allows researchers to leverage the unique features of Cas12 for specific applications in DNA editing.
6.Base Editing Kits:
Purpose: Facilitates base pair modifications without causing double-strand breaks, allowing precise changes in DNA sequences.
Description: Kits for performing base editing, a revolutionary technique for direct conversion of one DNA base pair to another.
7.RNAi Libraries:
Purpose: Collections of siRNAs or shRNAs for targeted gene silencing through RNA interference.
Description: Provides a library of small RNA molecules for researchers to study and modulate gene expression with high specificity.
8.Homologous Recombination Kits:
Purpose: Facilitates the introduction of specific genetic sequences into target genomes through homologous recombination.
Description: Kits enabling researchers to achieve precise genome modifications by promoting recombination events.
9.CRISPR-Cas9 Protein:
Purpose: In vitro genome editing applications using purified Cas9 protein.
Description: Allows researchers to perform precise genome editing outside of living cells for various experimental setups.