H4C6 Knockout cell line （PC-9）

The H4C6 Knockout cell line (PC-9) serves primarily in cancer research particularly within the study of non-small cell lung cancer (NSCLC) biology and therapeutic resistance mechanisms This cell line genetically modified to lack the H4C6 gene is specifically used to investigate tumor cell proliferation migration and sensitivity to various chemotherapeutics facilitating insights into the molecular pathways involved in NSCLC progression Researchers can implement the H4C6 Knockout cell line in workflows involving in vitro assays including proliferation and invasion studies as well as drug response evaluations

The practical benefits include the ability to discern the specific role of the H4C6 gene in oncogenic processes enabling the development of targeted therapies Additionally this cell line excels in CRISPR-mediated genome editing protocols allowing for straightforward manipulation of other genes followed by phenotypic analysis Enhanced understanding of resistance mechanisms via this model may direct more effective treatment regimens for patients with NSCLC