Cas9 Expressing Human breast adenocarcinoma cells

Catalog Number: GEC0083

Price:

$3000

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Specifications

Product Information
Product Name	Cas9 Expressing Human breast adenocarcinoma cells
Specification	1*10^6
System	endocrine system
Resistance	hygro
Cas9 expression detection	Provided
Cell name	MDA-MB-415-CAS9
Cell morphology	Epithelial like, adherent cells
passage ratio	1:2~1:4
Species expression gene	Human
Expressed Gene	Cas9

Properties
Construction method	Viral method
Mycoplasma detection	negative
Storage and transportation	Dry ice transportation; Store in liquid nitrogen
Culture system	90% L-15+10% FBS (recommended to use source well improved culture medium)

Overview

MDA-MB-415-CAS9 is a genetically modified breast cancer cell line designed for advanced biological research particularly in the study of oncogene function tumorigenesis and gene editing applications This product integrates the CAS9 endonuclease system enabling researchers to efficiently edit specific genomic loci within target cells facilitating the exploration of genetic modifications that drive cancer progression

The key function of MDA-MB-415-CAS9 lies in its ability to harness the CRISPR/Cas9 technology for precise genome editing By utilizing this sophisticated mechanism researchers can create knockouts or introduce specific mutations in genes of interest leading to comprehensive studies on the impact of genetic variations in tumor biology This capability not only enhances the understanding of cancer mechanisms but also opens avenues for developing targeted therapies and personalized medicine approaches

The scientific importance of MDA-MB-415-CAS9 extends to its applications in both fundamental research and clinical settings It serves as a valuable tool in drug discovery enabling the screening of novel therapeutics and the evaluation of drug resistance mechanisms Furthermore its utility in various preclinical studies allows for the identification of potential biomarkers informing treatment strategies in oncology

Compared to alternative models MDA-MB-415-CAS9 stands out due to its inherent ability to reflect the genetic and phenotypic heterogeneity typical of human breast tumors Its integration of CRISPR technology streamlines experimental workflows fostering efficient and reproducible results that can accelerate cancer research timelines

Researchers and clinicians will find MDA-MB-415-CAS9 indispensable as it offers a unique combination of versatility accuracy and relevance to current scientific inquiries As a leader in biological product development our company is dedicated to providing high-quality innovative tools that empower the scientific community to unlock new insights in health and disease ultimately contributing to informed therapeutic advancements

Application

MDA-MB-415-CAS9 is primarily utilized in cancer research particularly in the study of breast cancer This genetically engineered cell line serves as a model for investigating the efficacy of CRISPR-Cas9 gene-editing techniques to target oncogenes and tumor suppressor genes associated with breast cancer progression Researchers can implement MDA-MB-415-CAS9 within their experimental workflows by co-culturing these cells with CRISPR constructs designed to disrupt specific genes enabling assessment of functional outcomes through proliferation assays and therapeutic response evaluations

In therapeutic studies MDA-MB-415-CAS9 allows for the examination of personalized medicine strategies by accurately mimicking patient-specific tumor genetics The cell line’s responsiveness to various chemotherapeutic agents can be quantified providing valuable insights into resilience mechanisms and potential resistance pathways The practical benefits of using MDA-MB-415-CAS9 include increased efficiency in screening anticancer agents and the ability to validate gene-targeted therapies ultimately paving the way for innovative treatment options in clinical oncology Moreover its adaptability to specialized protocols such as knock-in or knock-out studies enhances its versatility in the landscape of molecular biology research

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Please note that all services are for research use only. Not intended for any clinical use.

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