Human CAR-T Cytokine Release Syndrome (CRS) 18-Plex Panel
Catalog Number: AKME078
Price: Online Inquiry
Catalog Number: AKME078
Price: Online Inquiry
Product Information | |
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Product Name | Human CAR-T Cytokine Release Syndrome (CRS) 18-Plex Panel |
Analytes | IL-2RA IL-1beta IL-6 IL-8 IL-10 MIP-1alpha MCP-1 IL-12p70 IFNgamma GM-CSF IL-4 IL-15 Reg3A Elafin ST-2 IL-17A TNFRI Granzyme B |
Reactivity | Human |
Detection Method | Flow Cytometry |
Assay Time | 2 hours |
1x Ab-conjugated beads (premixed) | S4P2 - anti-H IL-2RA, S4P3 - anti-H IL-1beta, S4P4 - anti-H IL-6, S4P6 - anti-H IL-8, S4P7 - anti-H IL-10, S4P9 - anti-H MIP-1alpha, S4P11 - anti-H MCP-1, S4P12 - anti-H IL-12p70, S5P2 - anti-H IFNgamma, S5P3 - anti-H GM-CSF, S5P4 - anti-H IL-4, S5P5 - anti-H IL-15, S5P6 - anti-H Reg3A, S5P7 - anti-H Elafin, S5P8 - anti-H ST-2, S5P9 - anti-H IL-17A, S5P10 - anti-H TNFRI, S5P12 - anti-H Granzyme B, |
2x Biotin-detection Ab (premixed) | Biotin - anti-H IL-2RA, Biotin - anti-H IL-1beta, Biotin - anti-H IL-6, Biotin - anti-H IL-8, Biotin - anti-H IL-10, Biotin - anti-H MIP-1alpha, Biotin - anti-H MCP-1, Biotin - anti-H IL-12p70, Biotin - anti-H IFNgamma, Biotin - anti-H GM-CSF, Biotin - anti-H IL-4, Biotin - anti-H IL-15, Biotin - anti-H Reg3A, Biotin - anti-H Elafin, Biotin - anti-H ST-2, Biotin - anti-H IL-17A, Biotin - anti-H TNFRI, Biotin - anti-H Granzyme B |
Buffers | 2x NR dAb Diluent. One vial containing 1.25 mL of biotin detection antibody diluent. |
Lyophilized Standard Mix | One vial containing lyophilized recombinant Elafin, GM-CSF, Granzyme B, IFNγ, IL-1β, IL-2RA, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-15, IL-17A, MCP-1, MIP-1α, Reg3A, ST-2, TNFRI. |
LLOQs | Elafin, < 50 pg/mL; GM-CSF, < 10 pg/mL; Granzyme B, < 20 pg/mL; IFNγ, < 10 pg/mL; IL-1β, < 10 pg/mL; IL-2RA, < 300 U/mL; IL-4, < 3 pg/mL; IL-6, < 10 pg/mL; IL-8, < 1 pg/mL; IL-10, < 5 pg/mL; IL-12p70, < 10 pg/mL; IL-15, < 10 pg/mL; IL-17A, < 10 pg/mL; MCP-1, < 5 pg/mL; MIP-1α, < 5 pg/mL; Reg3A, < 30 pg/mL; ST-2, < 5 pg/mL; TNFRI, < 10 pg/mL. |
ULOQs | Elafin, > 10,000 pg/mL; GM-CSF, > 5,000 pg/mL; Granzyme B, > 5,000 pg/mL; IFNγ, > 2,000 pg/mL; IL-1β, > 5,000 pg/mL; IL-2RA, > 150,000 U/mL; IL-4, > 1,000 pg/mL; IL-6, > 5,000 pg/mL; IL-8, > 1,000 pg/mL; IL-10, > 5,000 pg/mL; IL-12p70, > 2,000 pg/mL; IL-15, > 5,000 pg/mL; IL-17A, > 1,000 pg/mL; MCP-1, > 5,000 pg/mL; MIP-1α, > 2,000 pg/mL; Reg3A, > 10,000 pg/mL; ST-2, > 5,000 pg/mL; TNFRI, > 5,000 pg/mL. |
Intra-assay CV | < 10% |
Inter-assay CV | < 20% |
Please note that all services are for research use only. Not intended for any clinical use.
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