Linkers

Linkers are essential tools used in molecular biology and bioconjugation enabling the joining of different molecules or functional groups In the field of drug development linkers play a crucial role in the creation of antibody-drug conjugates (ADCs) where a therapeutic drug is attached to an antibody molecule This allows for targeted delivery of the drug to specific cells increasing efficacy while reducing systemic toxicity Linkers are also used in the construction of DNA or protein-based nanosystems facilitating the attachment of various components and enabling the assembly of complex structures for applications such as drug delivery imaging and sensing

In the field of proteomics linkers find applications in the synthesis of peptide and protein conjugates By connecting peptides or proteins to probe molecules such as fluorophores or affinity tags linkers enable the detection and analysis of specific proteins or protein modifications This aids in understanding protein function and dynamics as well as in the development of diagnostics and therapeutics

In the realm of materials science linkers are used in the synthesis of functionalized surfaces and coatings By attaching molecules with desired properties such as adhesion hydrophobicity or biocompatibility linkers enable the customization of material surfaces for applications in biomedicine electronics and other industries Linkers also play a crucial role in the synthesis of polymers allowing the incorporation of different functional groups and controlling the polymer's properties such as solubility flexibility and stability