Strain Metabolic Engineering

Background of Metabolic Engineering

Metabolic engineering is a rapidly growing field that involves the design and construction of microbial cells for the production of high-value compounds. The optimization of metabolic pathways is a crucial step in this process, as it can significantly improve the efficiency and accuracy of production.

CD Biosynsis offers comprehensive metabolic engineering and pathway optimization services to help you achieve these goals.

Figure 1. Genes chosen for modification and their positions in metabolic fluxes. (Hanke P., et al. 2023)

Services offering

Our metabolic engineering and pathway optimization services include:

Pathway Optimization

Metabolic Throughout Analysis

Metabolic Network Modeling

Advantages of Partnering with CD Biosynsis

At CD Biosynsis, we have extensive expertise in synthetic biology and a proven track record of delivering successful metabolic engineering projects. Our integrated approach combines cutting-edge technologies and customized solutions to optimize metabolic pathways and enhance the production of high-value compounds.

• Expertise in synthetic biology
• Integrated approach
• State-of-the-art technologies
• Customized solutions

Some of the specific technologies we use include:

• Genome-scale metabolic model construction: using advanced computational tools and methods to construct genome-scale metabolic models that can predict the behavior of microbial cells under different conditions.
• Multistep pathway optimization: We use a combination of computational and experimental approaches to optimize multistep metabolic pathways and improve the production of high-value compounds.
• Rate-limiting enzyme engineering: We design and engineer enzymes that are crucial for the production of high-value compounds, with the goal of improving their activity and specificity.
• Gene regulatory element designing: We design and engineer gene regulatory elements that can control the expression of genes involved in metabolic pathways, with the goal of improving the efficiency and accuracy of production.

Want to Learn More

If you are interested in learning more about our metabolic engineering and pathway optimization services, please contact us. Our team of experts will be happy to discuss your project and provide guidance on how we can help you achieve your goals.

Reference

1. Hanke P., et al. Engineering of increased L-Threonine production in bacteria by combinatorial cloning and machine learning. Metabolic Engineering Communications, 2023, 17: e00225.

Please note that all services are for research use only. Not intended for any clinical use.