PFKFB3 Knockout cell line （BEAS-2B）

PFKFB3 Knockout cell line (BEAS-2B) serves as a critical tool in cancer research and metabolic studies enabling scientists to investigate the role of the PFKFB3 enzyme in cellular metabolism and tumor progression This knockout cell line is primarily applied in experiments examining glucose metabolism glycolytic pathway alterations and their implications in oncogenesis

Researchers can implement this product in their workflows by employing standard gene editing techniques to analyze metabolic flux cellular proliferation and response to metabolic inhibitors Specific use cases include assessing the impact of PFKFB3 deficiency on cell viability migration and invasion assays in various cancer cell models

The practical benefits of utilizing this knockout cell line include enhanced understanding of tumor metabolism and identification of potential therapeutic targets which can lead to the development of novel anti-cancer strategies Furthermore this cell line excels in advanced experimental protocols such as metabolic tracing and gene expression analyses offering insights into the intricate interplay between metabolic pathways and cancer development