Thioredoxin inhibitors
Learn MoreProteasome inhibitors are a class of compounds that have gained significant attention in the field of cancer research and treatment These inhibitors target the proteasome a cellular complex responsible for breaking down proteins in cells By inhibiting this process proteasome inhibitors disrupt the normal protein degradation pathway leading to the accumulation of damaged or misfolded proteins and ultimately triggering cell death This targeted approach has shown promise in the treatment of various types of cancers making proteasome inhibitors a valuable tool in the fight against this devastating disease
Catalog Number | Chemical Name | CAS # | Price |
---|---|---|---|
BC-0682 | (-)-Epigallocatechin gallate | 989-51-5 | Online Inquiry |
BC-0693 | Celastrol | 34157-83-0 | Online Inquiry |
EI-0165 | Amastatin hydrochloride | 100938-10-1 | Online Inquiry |
EI-0494 | Calpain Inhibitor I, ALLN | 110044-82-1 | Online Inquiry |
EI-0495 | Calpain Inhibitor II, ALLM | 136632-32-1 | Online Inquiry |
EI-0513 | Carfilzomib | 868540-17-4 | Online Inquiry |
EI-0555 | CEP-18770 | 847499-27-8 | Online Inquiry |
EI-0621 | Clasto-Lactacystin β-lactone | 154226-60-5 | Online Inquiry |
EI-0624 | Clioquinol | 130-26-7 | Online Inquiry |
EI-0821 | Epoxomicin | 134381-21-8 | Online Inquiry |
EI-0975 | Fenbendazole | 43210-67-9 | Online Inquiry |
EI-1311 | Lactacystin (Natural) | 133343-34-7 | Online Inquiry |
EI-1416 | Marizomib | 437742-34-2 | Online Inquiry |
EI-1503 | MLN-9708 | 1239908-20-3 | Online Inquiry |
EI-1641 | ONX-0914 | 960374-59-8 | Online Inquiry |
Proteasome inhibitors have a wide range of applications in both research and medicine In the field of research they are commonly used to study the role of protein degradation in various biological processes By inhibiting the proteasome scientists can better understand how proteins are regulated and degraded which can provide valuable insights into many diseases and conditions
In medicine proteasome inhibitors are used as a targeted therapy for certain types of cancer By blocking the proteasome's function these inhibitors prevent the breakdown of proteins that control cell growth and division leading to the death of cancer cells This approach has shown significant success in treating multiple myeloma and mantle cell lymphoma and research is ongoing to explore their potential in treating other types of cancer
Additionally proteasome inhibitors are being investigated for their potential in treating autoimmune diseases and neurodegenerative disorders By selectively degrading specific proteins involved in these conditions proteasome inhibitors have the potential to slow or halt disease progression and alleviate symptoms
Overall proteasome inhibitors have emerged as a valuable tool in both research and medicine with the potential to make significant contributions to our understanding and treatment of various diseases
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