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Protein Analysis Services

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We offer a comprehensive suite of Protein Analysis Services designed to meet the diverse needs of our clients in pharmaceutical research, biotechnology, and academic institutions. Our services cover a wide range of analytical techniques to assess protein structure, function, purity, and stability. With state-of-the-art equipment and a team of experienced scientists, we provide reliable and detailed protein analysis to support your research and development projects.

Schematic representation of various types of tandem mass spectrometry experiments(B Domon, et al.,2006)

Overview Service Process Case Examples and Solutions Frequently Asked Questions

Overview

Protein analysis is a critical component of any protein-related research and development project. Accurate and detailed analysis provides insights into the protein's structure, functionality, and quality, which are essential for applications such as drug development, therapeutic protein production, and biochemical research. Our Protein Analysis Services encompass a variety of techniques and methodologies to ensure comprehensive and accurate results.

Our Service Highlights:

  • High Precision: Accurate measurements and analysis to support critical decision-making.
  • Tailored Solutions: Customized analysis strategies to meet the specific requirements of each project.
  • End-to-End Support: From sample preparation to data interpretation, we provide comprehensive support.

Comparison of Protein Analysis Techniques

Technique Description Advantages Applications
Mass Spectrometry (MS) Analyzes the mass and composition of proteins. High sensitivity, detailed molecular information. Protein identification, post-translational modifications, proteomics.
High-Performance Liquid Chromatography (HPLC) Separates and quantifies protein mixtures. High resolution, reproducibility. Protein purity analysis, quantification, peptide mapping.
Circular Dichroism (CD) Spectroscopy Measures protein secondary structure. Non-destructive, quick analysis. Structural studies, conformational analysis.
Nuclear Magnetic Resonance (NMR) Spectroscopy Determines protein structure in solution. Detailed structural information, dynamics. Structural biology, interaction studies.
X-ray Crystallography Determines atomic structure of crystallized proteins. High resolution, detailed atomic structure. Structural biology, drug design.
SDS-PAGE Separates proteins based on molecular weight. Simple, cost-effective. Protein purity, molecular weight determination.
Western Blotting Detects specific proteins in a sample. High specificity, quantitative analysis. Protein expression, post-translational modifications.

Service Process

  1. Project Consultation: Collaborating with clients to understand their specific protein analysis goals, including target proteins, desired analytical techniques, and application requirements.
  2. Sample Preparation: Preparing protein samples using optimized protocols to ensure accurate and reproducible results.
  3. Analytical Testing: Performing the selected analytical techniques using state-of-the-art equipment and methodologies.
  4. Data Analysis: Analyzing the data obtained to provide detailed insights into the protein's structure, function, and quality.
  5. Reporting: Delivering comprehensive reports with detailed results, interpretations, and recommendations.
  6. Technical Support: Providing ongoing support and consultation to help clients interpret the results and apply them to their projects.

For more information on our Protein Analysis Services, please fill out our online inquiry form. One of our specialists will get back to you promptly to discuss your specific needs.

Case Examples and Solutions

Case Examples Solutions We Offer
Drug Development: Characterizing therapeutic proteins for stability and activity. Using MS, HPLC, and NMR to analyze protein structure, purity, and stability, ensuring the therapeutic efficacy and safety.
Biopharmaceutical Research: Analyzing monoclonal antibodies for post-translational modifications. Employing MS and Western blotting to identify and quantify post-translational modifications critical for antibody function.
Protein Engineering: Assessing structural changes in engineered proteins. Utilizing CD spectroscopy and X-ray crystallography to study conformational changes and structural integrity.
Proteomics: Identifying and quantifying proteins in complex mixtures. Applying advanced MS techniques for comprehensive proteomic analysis, providing insights into protein expression and regulation.
Quality Control: Ensuring the purity and consistency of produced proteins. Conducting HPLC and SDS-PAGE to verify protein purity and molecular weight, supporting quality control processes.
Structural Biology: Determining the structure of novel proteins. Using NMR and X-ray crystallography to elucidate the atomic structure, aiding in the understanding of protein function and interaction.

Frequently Asked Questions

Q: What protein analysis services do you offer?

A: We offer a wide range of protein analysis services, including mass spectrometry, HPLC, circular dichroism spectroscopy, NMR spectroscopy, X-ray crystallography, SDS-PAGE, and Western blotting.

Q: How do you ensure the accuracy of your protein analysis?

A: We use state-of-the-art equipment and methodologies, coupled with rigorous quality control procedures, to ensure high accuracy and reliability in our protein analysis.

Q: Can you customize your analysis to meet specific project needs?

A: Yes, we provide tailored analysis strategies to meet the specific requirements of each project, ensuring the most relevant and accurate results.

Q: How do you handle sample preparation?

A: We use optimized protocols for sample preparation to ensure that the samples are suitable for accurate and reproducible analysis.

Q: What kind of reports do you provide?

A: We deliver comprehensive reports that include detailed results, data interpretations, and recommendations to help clients make informed decisions.

Q: What support do you offer post-analysis?

A: We offer ongoing technical support and consultation to help clients interpret the results and apply them to their projects effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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