Synthetic Genomics

CD Biosynsis offers customized synthetic genomics solutions to help researchers around the world facilitate their cutting-edge research and overcome the challenges. We provide advanced techniques and powerful tools to help our customers solve any problems encountered in their projects and bring breakthrough ideas to fruition.

Introduction to Synthetic Genomics

In the past, one of the major challenges in biology was DNA sequence determination. Today, the development of next-generation sequencing technology has dramatically reduced sequencing time. The increasing number of genome sequences in public databases indicates that scientists are now doing well in reading genomes. However, the ability to write synthetic DNA sequences is also required to better understand the grammar of life. Recently, with the increased ability to synthesize longer DNA segments and the reduced cost of DNA synthesis, it has become possible to design and construct whole synthetic chromosomes in the megabase range, which also allows scientists to identify their functions in vivo. Synthetic genomics has opened up new paradigms for studying the fundamental principles of genomes and engineering novel biological functions.

As an intersection of synthetic biology and systems biology, synthetic genomics is defined as an emerging field of engineering and manipulating an organism's genetic material at the genome level. Synthetic genomics aims to genetically modify existing life forms, or create new organisms and biological systems through artificial gene synthesis to satisfy human needs. Techniques for generating chemically-synthesized genomes are incorporated into synthetic genomics, which allows for numerous simultaneous changes to the genetic materials. As a result, synthetic biology is becoming increasingly dependent on and integrated with synthetic genomics.

Figure 1. Milestones in DNA reading and writing. (Schindler D & Dai J, Cai Y., 2018)

Applications

Our Solutions

CD Biosynsis offers integrated synthetic genomics solutions for specific purposes and a wide range of applications to help customers overcome the challenges of their synthetic biology projects.

CD Biosynsis is committed to developing services and products that cover a wide range of steps in the synthetic biology workflow. We are confident in the validity and reproducibility of the results we deliver because all of our services and products are based on reliable technologies and optimized protocols to meet high standards.

To start your synthetic biology projects, please feel free to contact us for more details. Our experienced scientific team of biologists, bioinformatics, and chemists are available for on-demand customer assistance to help you with any concerns you may have.

References

1. Schindler D & Dai J, Cai Y. Synthetic genomics: a new venture to dissect genome fundamentals and engineer new functions. Current opinion in chemical biology, 2018, 46: 56-62.
2. Konig H, et al. Synthetic genomics and synthetic biology applications between hopes and concerns. Current genomics, 2013, 14(1): 11-24.

Please note that all services are for research use only. Not intended for any clinical use.