Bioremediation

CD Biosynsis provides our advanced technologies in synthetic biology to help our customers create powerful microorganisms or plants for bioremediation of contamination in the environment in response to the growing problem of environmental pollution.

Synthetic Biology and Bioremediation

Bioremediation is a process that uses biological activity to promote degradation or remove pollutants from the environment. It involves the use of plants or microorganisms to deal with the environment polluted by organic molecules that are difficult to decompose. Compared to other physicochemical methods, using the metabolic capacity of plants, microorganisms, or microbial enzymes to degrade environmental contamination provides a sustainable and safe alternative. However, it is not easy to solve the problem of environmental pollution in practice. It is an effective and feasible method to optimize the bioremediation process of environmental pollutants by adding natural microorganisms containing catabolic genes or genetically modified microorganisms. Advances in synthetic biology enable the design of tailor-made organisms for bioremediation. Using synthetic biology techniques, we can design and construct new biological components to produce new strains with the properties required for bioremediation processes. In addition to microorganisms, many plants can be engineered through synthetic biology techniques to enhance their ability to absorb and immobilize pollutants in the environment.

Figure 1. Schematic demonstrating how synbio techniques could be applied to develop and enhance bioremediation with plants and microbes. (Rylott EL, et al., 2020)

How We Can Help

CD Biosynsis provides our expertise and advanced technologies to help our customers develop synthetic biology strategies to facilitate environmental remediation of emerging pollutants. Our scientists can modify the metabolic pathways of microorganisms to construct high-quality engineered strains suitable for bioremediation to cope with different contaminated environments.

Development of Synthetic Biology Chassis for Bioremediation

Our expertise in bacterial synthetic biology, fungal synthetic biology, algal synthetic biology, and plant synthetic biology has allowed us to develop effective genetic tools and metabolic engineering strategies that enable different types of microorganisms and plants to acquire desirable properties and become useful tools for dealing with different environmental contaminants. The following are bacteria, fungi, algae, and plants that we are capable of developing into synthetic biology chassis for bioremediation. If you are interested in other microbial strains or plants, please fill out our online inquiry form and tell us more about your project.

Our Key Services

• Targeted genes were engineered into rhizosphere-colonizing bacteria and Arabidopsis thaliana to generate microorganisms and plant species that were better able to degrade RDX (an environmental contaminant of military munition components).
• Creation of recombinant E. coli with improved metal binding capacity for the mitigation of heavy metal contamination in the environment.
• Modification of microorganisms and biofilms to produce engineered microorganisms for the treatment of organic pollutants in the environment.

Deliverables

• Engineered microorganisms or plants that can be used for bioremediation.
• High-quality microbial enzyme products for bioremediation, including laccases, hydrolases, dehalogenases, dehydrogenases, proteases, lipases, etc.

Want to Learn More?

With our professional research team and the most comprehensive technology platform in the field of synthetic biology, CD Biosynsis provides convenient and efficient one-stop service to our global customers. We are able to design personalized microbial and plant solutions to support clean-up with bioremediation following environmental disasters. We have successfully developed several microbial engineering systems containing strong oxidative enzymes for bioremediation for our customers.

After establishing a clear goal and developing a design strategy, the following outstanding capabilities can facilitate the development of synthetic biology-based solutions for bioremediation.

CD Biosynsis provides fast turnaround, high-quality services at competitive prices for worldwide customers. If you are interested in our services, please contact us for more detailed information.

References

1. Rylott EL.;Bruce NC. How synthetic biology can help bioremediation. Curr Opin Chem Biol. 2020, 58: 86-95.
2. Pieper DH; Reineke W. Engineering bacteria for bioremediation. Curr Opin Biotechnol. 2000, 11(3): 262-70.
3. Azubuike CC, et al. Bioremediation techniques-classification based on site of application: principles, advantages, limitations and prospects. World J Microbiol Biotechnol. 2016, 32(11): 180.

Please note that all services are for research use only. Not intended for any clinical use.