CD Biosynsis offers the best gene editing service. We are using cutting edge CRISPR/Cas9 technology to offer customers accurate and powerful gene editing solutions. These providers provide all sorts of gene editing, from gene knockouts to gene knockins, homologous recombination and transposon-based gene editing. In functional genomics, metabolic engineering, synthetic biology and industrial biotechnology, the gene editing services are commonplace. With such services, scientists can trace gene function with high accuracy, tune metabolism, and find novel biosynthetic routes. In addition, CD Biosynsis also offers custom gene editing for customers’ ‘specific requirements for specific research requirements.
Get a QuoteGene Editing Technology is a technology used to accurately modify specific genes in an organism's genome. This technology uses specific enzyme systems, such as CRISPR-Cas9, ZFN (zinc finger nucleases) and TALEN (transcription activator-like effector nucleases), to cut at specific locations in the DNA sequence, thereby achieving gene insertion, deletion or replacement operations.
Used for precise genome modifications, such as correcting genetic mutations, developing disease models, and studying gene functions.
Allows for precise base changes without causing double-strand breaks, useful for correcting single-point mutations.
Combines the advantages of base editing and HDR, enabling more complex edits with higher precision.
CRISPRa (activation) and CRISPRi (interference) use catalytically inactive Cas9 (dCas9) to regulate gene expression without altering the DNA sequence.
TALENs are more flexible in targeting DNA sequences but are larger in size, making delivery more challenging.
ZFNs are highly specific but often more difficult to design and may have higher off-target effects and cell toxicity.
Human and Mouse Cell Lines
Commonly used for disease modeling, drug discovery, and basic research.
Primary T Cells
Used in CAR-T immunotherapy development.
Provide disease-specific models for drug discovery and regenerative medicine.
Used for basic genetic studies and metabolic engineering.
Optimizing metabolic pathways, enhancing antibiotic production, developing microbial biosensors, and studying bacterial gene functions
Widely used for generating genetically modified models for studying human diseases.
Introduce a frameshift mutation in a single gene to study its function.
Double Gene Knockout
Simultaneously knockout two genes to study their combined effects.
Insert a reporter gene (e.g., GFP, luciferase) to monitor gene expression or cellular processes.
Corrective Gene Insertion
Insert a corrected version of a gene to study genetic diseases.
CRISPRa (Activation)
Upregulate gene expression using dCas9 fused to transcriptional activators.
CRISPRi (Interference)
Downregulate gene expression using dCas9 fused to transcriptional repressors.
CRISPRoff/CRISPRon
Epigenetically modify and silence genes without editing the underlying genome, with the ability to reactivate gene expression using a different fusion protein.
Generate cell lines that stably express Cas9 for long-term gene editing experiments.
Create cell lines with specific genetic modifications according to customer specifications.
sgRNA Library
Design and construct libraries of sgRNAs for high-throughput screening of gene functions.
pegRNA Library
Enable precise editing with pegRNA up to 220 nt for more complex genetic modifications.
The general workflow for gene editing services involves several key steps, ensuring precise and efficient modifications to the target genome.
Demand communication and plan formulation
Sign the contract
Experimental execution
Results delivery and analysis
Customers first need to communicate with CD Biosynsis's professional technical consultants to clarify their gene editing needs, including target genes, editing types (such as knock-out, knock-in or modification) and specific experimental requirements.
According to customer needs, CD Biosynsis's technical team will conduct personalized project analysis and develop detailed experimental plans.
After confirming the plan, both parties will sign a gene editing service contract to clarify the project details, fees and delivery time.
After completing the gene editing, CD Biosynsis will provide customers with detailed experimental reports, including gene editing efficiency, cell phenotypic changes and possible off-target effect analysis.
Customers can further research or apply these gene-edited cell lines based on the data provided.
Efficient gene editing
We use advanced CRISPR/Cas9 gene editing technology to efficiently perform gene knock-out, knock-in and modification operations. This technology not only improves the success rate of gene editing, but also significantly shortens the experimental cycle, allowing customers to obtain research results faster.
Comprehensive service process
We provide full-process services from gene editing strategy design, experimental operations to data analysis. This includes the construction of gene editing vectors, lentivirus packaging, animal model generation, etc., to ensure that customers can receive high-quality research support.
Customization and flexibility
We are able to provide customized gene editing solutions based on our customers 'specific needs, including gene editing services for different cell lines and animal models. This flexibility allows our services to meet complex scientific needs.
Global service network and experience accumulation
Our service scope covers the world. Rich case experience and a global service network enable us to provide stable and efficient gene editing services to our customers.
Gene editing services can do many things from basic research to clinical applications. These are some of the main activities gene editing services can offer:
Drug discovery
Gene editing software is important in the discovery of drug. Scientists can use gene editing tools to generate disease models, investigate phenotypes of certain mutations, and create more accurate drug screening tests.
Genes function research
Scientists using gene editing modify certain genes to discover how they function and how they influence living things. For example, studies of the way that genes impact animals by knocking them out or in.
Agriculture improvements
It is using gene editing technology to improve plants and animals, such as crop production, food quality, or disease resistance. An example that can change sugarcane growth habits.
Basic biology research
Gene editing platforms like CRISPR-Cas9 system are widely used in basic biology to study gene expression regulation, epigenetics, and function.
Synthetic biology
Gene editing technology can also be applied in microorganism biology to optimize microorganism metabolic systems or their productivity in industries.
The results of monoclonal sequencing showed that nested peaks began to appear at the sgRNA site, and the verification of monoclonal Fast NGS sequencing showed that 1 bp was knocked out, resulting in a frame-shift mutation.
"Working with CD Biosynsis for gene editing has been nothing less than revolutionary. Their CRISPR/Cas9 expertise enabled us to make fine genetic changes in our model organisms, significantly accelerating our studies of genetic disease. The responsiveness and technical support from the team were unmatched, and we were able to meet our project milestones without a hitch. I highly recommend CD Biosynsis for their cutting-edge technology and attention to detail."
Dr. Emily Carter, Genomics Institute
"We commissioned CD Biosynsis to support an intricate gene editing project with multiple targets. Their talent in producing high-quality work in a short period of time was impressive. Their solutions were custom made to suit our needs, and they went above and beyond to ensure our experiments worked. Their support has been a great asset to our research department and we look forward to further working with them."
Dr. Raj Patel, Principal Investigator, Department of Molecular Biology
"As a pharmaceutical company working to discover new cancer therapies, we require accurate, trustworthy gene editing solutions. CD Biosynsis did more than what we expected when it came to providing strong, accurate CRISPR/Cas9 solutions for our preclinical research. Their technical support team was excellent and responsive, and they quickly replied to our questions. This alliance has been pivotal in helping us move our drug pipeline forward. Thank you, CD Biosynsis, for your amazing service!"
Dr. Clara Rodriguez, Chief Scientist, AstraZeneca Pharmaceuticals, Spain
"Our experience with CD Biosynsis has been a total success. From experimental design to data collection, they made sure that our gene editing experiment went off without a hitch. They have put their advanced technology and synthetic biology skills to the test in our studies of metabolic pathways. We appreciate their commitment and are excited to keep working together."
Dr. Hiroshi Tanaka, Research Fellow, Department of Bioengineering
"When we were looking for an experienced partner for our gene editing work on rare disease, CD Biosynsis stood out. The quality of their work, both for accuracy and for innovation, was evident during our time working together. The high-quality results they produced have been instrumental in pushing the field of genetics on rare diseases forward. Their service has changed our research for the better, and we would recommend them to any institution that wants the best gene editing service."
Dr. Sophie Dubois, Director, Rare Diseases Research, Sanofi, France
How long is the cycle of gene editing services?
The delivery cycle of gene editing services varies by project. For example:
What are the technical support for gene editing services?
We provide comprehensive technical support, including pre-sales technical service plan design, information feedback during the experimental process, and after-sales technical consultation and return visit services. In addition, we also provide customized technical services, such as targeted evolution of AAV vector capsid, mRNA vector gene delivery solutions, library construction, promoter evolution and screening, etc.
How much does gene editing services cost?
Gene editing services vary in terms of cost and complexity of the project, technology used etc. Gene editing outsourcing saves organizations money on equipment, staff and training. We offer customizable quote schedules for customers to evaluate in-depth.
Do gene editing services meet regulatory standards?
We adhere to the regulatory standards of CRISPR gene editing to help ensure that projects of our customers will meet all the applicable regulations and standards (e.g., clinical trials) and not delay the project.
What to look for when selecting the best gene editing service?
We provide various gene editing services such as CRISPR-sgRNA library generation, stable transformation cell line generation, gene knockout cell line generation, and gene point mutation cell line generation. Users are free to select the type of service that suits their research.
What can make gene editing services safe?
We prioritize safety in our services and every activity is conducted under the ethical and safety guidelines. We also provide experimental reports and data analysis to make sure the outcomes are accurate.
What do you want to be from you?
You can reach us using the following ways:
Does gene editing allow customisability?
Yes, we offer very customised gene editing solutions such as AAV vector capsid directed evolution, mRNA vector gene delivery, library creation, promoter evolution and screening, etc.
What is the process for keeping data private and confidential?
We adhere to the data privacy policy completely, and all customer data and experimental data are kept confidential.
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Genetics research is an important branch of biology. It determines organism's genetic features and genetic processes through genetic DNA, RNA, and so on. Genetics not only makes it possible to find out about the genetic origins and diversity of life, but affects almost every area of medicine, agriculture and ecology.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.