Strain Improvement Service

Background of Strain Improvement

Strain improvement is a critical aspect of synthetic biology that involves the targeted enhancement of microorganisms or cell lines for specific applications. It revolves around modifying the genetic, metabolic, and physiological characteristics of these organisms to optimize their performance in various industrial, medical, or research contexts.

CD Biosynsis offers a comprehensive range of services for strain engineering, including strain selection, advanced hybridization techniques, strain characterization, and scale-up and optimization. Our team of experts uses a systematic approach to identify the most suitable strains for hybridization based on the desired properties and applications. We leverage cutting-edge technologies and techniques, such as CRISPR-Cas9-mediated genome editing, to optimize the hybrid strains for maximum performance.

Figure 1. Components of precision engineering technology for microbial strain improvement. (Saxena S. 2015)

Services offering

Phenotypic Screening and Selection in Synthetic Biology

Strain Domestication

Adaptive Evolution in Strains

Mutagenesis in Strains

Strain Hybridization

Advantages of Partnering with CD Biosynsis

Several advantages that set us apart from other providers of strain improvement services. Our team of experts has extensive experience in strain engineering for various applications, including industrial biotechnology, agriculture, and medicine. We leverage cutting-edge technologies and techniques to ensure that our clients receive the highest quality services.

Here are some of the key advantages of choosing CD Biosynsis for your strain improvement needs:

• Comprehensive Strain Selection: Our team of experts uses a systematic approach to identify the most suitable strains for hybridization based on the desired properties and applications. We have access to a wide range of microbial strains, including bacteria, yeast, and fungi, which enables us to select the best strains for each specific application.
• Advanced Hybridization Techniques: We use a variety of hybridization techniques, including traditional methods such as conjugation, transformation, and transduction, as well as modern techniques such as CRISPR-Cas9-mediated genome editing.
• Extensive Strain Characterization: We use various techniques such as DNA sequencing, PCR, and phenotypic analysis to characterize the hybrid strains. This enables us to identify any potential issues and optimize the strains for maximum performance.
• Documentation and Quality Control: We ensure that the documentation of the strains is of the highest quality and that the strains are thoroughly tested and characterized before they are delivered to the clients.
• Customization: We offer customized services that are tailored to the specific needs of each client.

Want to Learn More

By leveraging our expertise, cutting-edge technologies, and comprehensive services, CD Biosynsis is the ideal partner for any organization looking to engineer microbial strains for various applications. Contact us today to learn more about our strain improvement services and how we can help you achieve your goals.

Reference

1. Saxena S. Strategies of Strain Improvement of Industrial Microbes. Applied Microbiology, 2015: 155-171.

Please note that all services are for research use only. Not intended for any clinical use.