Strain Engineering for Amino Acid

CD Biosynsis focuses on optimizing amino acid biosynthesis processes using advanced technologies and innovative methods, and we look forward to providing optimal solutions for our customers' amino acid biosynthesis projects.

Background of Amino Acid Biosynthesis

Amino acids are extremely important substances in the survival and development of the organism. Amino acids and their derivatives have been widely used in the food, chemical, feed cosmetic, and pharmaceutical industries. At present, protein hydrolysis, enzymatic synthesis, and microbial fermentation are mainly used to produce amino acids. With the development and application of modern biotechnology, bioinformatics, synthetic biology and metabolic engineering, the low-cost and high-efficiency production of amino acids has become a hot spot in synthetic biology research.

Figure 1. Biosynthesis pathway of amino acids. (Hirasawa T, et al., 2016)

Service Offering

As a technology company in the field of synthetic biology, our scientists have a long history of exploring ways to improve the yield of amino acids synthesized by microbial fermentation. Our focus includes the level of precursor material supply, feedback inhibition of key enzymes, the deterrent effect of blocking proteins, the relationship between strain growth and product production, the introduction of exogenous-related enzymes, and the optimization of culture media. We expect to break through the barriers to scaling up amino acid production through the above approaches. Currently, we can offer the following types of amino acids that are synthesized based on synthetic biology.

Strain Engineering for Alanine

Strain Engineering for Glutamate

Strain Engineering for Aspartic Acid

Strain Engineering for Lysine

Strain Engineering for Tryptophan

Strain Engineering for Valine

Strain Engineering for Arginine

Strain Engineering for Phenylalanine

Strain Engineering for Tyrosine

Why Choose Us?

• We have established a precision fermentation platform that enables dynamic regulation of microbial fermentation processes based on temperature, inducer and other factors.
• We are able to provide a one-stop service to help our customers solve the challenges in the entire amino acid production process from strain mutagenesis to target product extraction process optimization.
• We are committed to improving the efficiency of metabolic engineering breeding by developing integrated analysis methods for multi-omics data and refining computer simulation techniques.

Solutions Related to Amino Acid Biosynthesis

• Synthetic Genomics
• Protein Synthetic Biology
• Bacterial Synthetic Biology
• Fungal Synthetic Biology
• Synthetic Enzymology

Want to Learn More?

CD Biosynsis provides the most comprehensive and efficient solutions for synthetic biology workflows. We are committed to helping our customers solve all problems encountered in amino acid production to advance their applications in a wide range of fields. Each of our deliverables will undergo a rigorous quality inspection test to ensure the reliability and accuracy of the results. If you are interested in our services or have any further questions, please do not hesitate to contact us.

Reference

1. Hirasawa T, Shimizu H. Recent advances in amino acid production by microbial cells. Curr Opin Biotechnol. 2016 Dec; 42: 133-146.

Please note that all services are for research use only. Not intended for any clinical use.